25 years female presented with malar rash on the face, fever, painful joints of fingers. On examination she has tenderness in small joints of both hands without deformity. Laboratory investigations reveals pancytopenia, urine routine- hematuria and proteinuria, and ANA ++ a) What is your probable diagnosis? Give reasons. 2 mark b) Write about the pathogenesis of the disease? 5mark c) Write in brief about central and peripheral tolerance. 3 mark